Abstract The liver is one of the most vital organs of the human body responsible for metabolism, detoxification, digestion of fats through bile secretion, regulation of blood sugar and storage of essential vitamins and minerals. In recent years liver diseases have become increasingly prevalent worldwide. Conditions like fatty liver disease, hepatitis, cirrhosis and liver fibrosis are now being reported at…
Introduction Fatty liver disease is a common metabolic condition characterized by excessive accumulation of fat in the liver. It is frequently associated with obesity, insulin resistance, type 2 diabetes, abnormal cholesterol or triglyceride levels, and a sedentary lifestyle. Alcohol consumption can also contribute to liver fat accumulation and liver injury. In its early stages, fatty liver disease may cause no…
Chronic liver diseases often progress through stages of inflammation, fibrosis, and ultimately cirrhosis. Detecting fibrosis at an early stage is critical because the process may be partially reversible if the underlying cause is addressed. Historically, liver biopsy has been considered the reference standard for fibrosis evaluation. However, biopsy has several drawbacks, including invasiveness, sampling error, and difficulty in performing repeated…
Indocyanine Green (ICG) Clearance Test Abstract The liver plays a critical role in metabolism, detoxification, synthesis of proteins, and excretion of metabolic waste. Evaluating the functional capacity of the liver is essential for diagnosing liver disease and determining the safety of surgical interventions involving hepatic tissue. Traditional liver function tests such as bilirubin, transaminases, and albumin provide indirect information about…
Abstract The liver performs numerous vital physiological functions including detoxification, protein synthesis, bile production, and metabolic regulation. Chronic liver diseases gradually impair these functions through inflammation, fibrosis, and cellular damage. Early detection of liver pathology is critical for preventing disease progression and improving patient outcomes. Traditional liver function tests such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and bilirubin provide…
Abstract Fatty Liver disease is a very common liver disease that is affecting a large number of the population. It occurs due to excess fat accumulation in the liver cells. It is also medically known as hepatic steatosis. It is also known as a silent epidemic as it develops silently and the symptoms are either very few or no symptoms…