Chronic liver diseases often progress through stages of inflammation, fibrosis, and ultimately cirrhosis. Detecting fibrosis at an early stage is critical because the process may be partially reversible if the underlying cause is addressed. Historically, liver biopsy has been considered the reference standard for fibrosis evaluation. However, biopsy has several drawbacks, including invasiveness, sampling error, and difficulty in performing repeated…
Indocyanine Green (ICG) Clearance Test Abstract The liver plays a critical role in metabolism, detoxification, synthesis of proteins, and excretion of metabolic waste. Evaluating the functional capacity of the liver is essential for diagnosing liver disease and determining the safety of surgical interventions involving hepatic tissue. Traditional liver function tests such as bilirubin, transaminases, and albumin provide indirect information about…
Abstract The liver performs numerous vital physiological functions including detoxification, protein synthesis, bile production, and metabolic regulation. Chronic liver diseases gradually impair these functions through inflammation, fibrosis, and cellular damage. Early detection of liver pathology is critical for preventing disease progression and improving patient outcomes. Traditional liver function tests such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and bilirubin provide…
Abstract Fatty Liver disease is a very common liver disease that is affecting a large number of the population. It occurs due to excess fat accumulation in the liver cells. It is also medically known as hepatic steatosis. It is also known as a silent epidemic as it develops silently and the symptoms are either very few or no symptoms…
ABSTRACT Fatty liver disease is a major health concern. Fatty liver is a common problem amongst children as well as adults. Fatty liver disease is a common hepatic disorder that is characterized by the abnormal accumulation of fat within liver cells. Fatty liver accounts for 5-10 percent extra weight of the liver. It is closely associated with obesity, diabetes, sedentary…
ABSTRACT The liver is located in the upper right part of the abdomen. The weight of the liver is 3 pounds (1.36078kg). The liver regulates most of the chemical levels and excretes bile. The liver is an organ which is responsible for supporting metabolism, immunity, digestion, detoxification and vitamin storage. The liver is the only organ in the human body…
Abstract Fatty liver is becoming one of the most common liver disorders not only in India but globally. This is due to changes in the lifestyle and food that we consume in the present millennium. Both Non-Alcoholic fatty liver (NAFLD) and Alcoholic fatty liver are becoming more frequent amongst those who visit the outpatient department. This is due to rising…
Abstract Ayurveda, an ancient system of medicine which originates in India. It is a knowledge which helps us to lead a healthy life by making the right decision for body and mind. But due to altered lifestyle and faulty food habits liver disorders are commonly occurring in modern India. Healthy liver is very essential for overall health and well being…
ABSTRACT Progressive familial intrahepatic cholestasis (PFIC) is a term used to describe a diverse set of juvenile autosomal recessive diseases that affect bile production and manifest as cholestasis of hepatocellular origin. People with conditions like portal hypertension, hepatosplenomegaly, jaundice, or acute itching are specifically targeted. This illness primarily results in cirrhosis and an urgent need for a liver transplant. Progressive…