ABSTRACT The PIVKA-II Test, also known as Des-gamma-carboxy Prothrombin (DCP), is an important biochemical marker used primarily in the diagnosis and monitoring of liver diseases. It is widely recognized as a tumor marker for Hepatocellular Carcinoma, the most common type of primary liver cancer. Normally, PIVKA-II levels remain low in healthy individuals, typically below 40 mAU/mL. However, elevated levels may…
Chronic liver diseases often progress through stages of inflammation, fibrosis, and ultimately cirrhosis. Detecting fibrosis at an early stage is critical because the process may be partially reversible if the underlying cause is addressed. Historically, liver biopsy has been considered the reference standard for fibrosis evaluation. However, biopsy has several drawbacks, including invasiveness, sampling error, and difficulty in performing repeated…
Indocyanine Green (ICG) Clearance Test Abstract The liver plays a critical role in metabolism, detoxification, synthesis of proteins, and excretion of metabolic waste. Evaluating the functional capacity of the liver is essential for diagnosing liver disease and determining the safety of surgical interventions involving hepatic tissue. Traditional liver function tests such as bilirubin, transaminases, and albumin provide indirect information about…
Abstract The liver performs numerous vital physiological functions including detoxification, protein synthesis, bile production, and metabolic regulation. Chronic liver diseases gradually impair these functions through inflammation, fibrosis, and cellular damage. Early detection of liver pathology is critical for preventing disease progression and improving patient outcomes. Traditional liver function tests such as alanine aminotransferase (ALT), aspartate aminotransferase (AST), and bilirubin provide…
Abstract Fatty Liver disease is a very common liver disease that is affecting a large number of the population. It occurs due to excess fat accumulation in the liver cells. It is also medically known as hepatic steatosis. It is also known as a silent epidemic as it develops silently and the symptoms are either very few or no symptoms…
ABSTRACT Fatty liver disease is a major health concern. Fatty liver is a common problem amongst children as well as adults. Fatty liver disease is a common hepatic disorder that is characterized by the abnormal accumulation of fat within liver cells. Fatty liver accounts for 5-10 percent extra weight of the liver. It is closely associated with obesity, diabetes, sedentary…
Abstract The liver is a vital organ responsible for detoxification, metabolism, and digestion. Various factors like poor diet, alcohol consumption, and infections can lead to liver diseases, including liver cirrhosis. Ayurveda offers natural remedies that help maintain liver health and prevent failure. Introduction The liver plays a crucial role in maintaining overall health. However, modern lifestyle choices often lead to…