Wiskott Aldrich Syndrome Treatment & Management in Ayurveda

Abstract

Wiskott Aldrich syndrome is a genetic disorder that leads to decreased blood clotting ability and immunological deficiency. Wiskott Aldrich syndrome also known as WAS is caused due to genetic mutation in a specific WAS genes which mainly affects males. This disorder is inherited in an X-linked manner that is known to have a good prognosis with passing time due to improved methods of treatment and technology. As there is a reduction in blood clotting ability of the body hence the signs and symptoms which observed are related to it like the decreased number of platelets causing easy bruising and bleeding, due to low immunity person is more prone to infections and inflammatory disorders, also the risk of cancer like lymphomas are increased. Let us learn all about WAS disease, its signs and symptoms, causes, diagnosis, and herbal management of Wiskott Aldrich disease by Planet Ayurveda’s herbal formulations.

INTRODUCTION

Mutation in WAS gene not only causes Wiskott Aldrich syndrome but also causes X-linked neutropenia and X-linked thrombocytopenia and all these three together are called WAS-related disorders. These three disorders can be difficult to differential diagnose as they have overlapping symptoms, however Wiskott Aldrich syndrome is the severe one in all three of them. Severity of the Wiskott Aldrich syndrome depends upon the severity of deficiency of the WASP, i.e. Wiskott Aldrich syndrome protein. WAS is a are disease which is inherited in the recessive pattern through the X-gene.

SIGNS AND SYMPTOMS

As it is inherited in the X-linked recessive pattern, so the males are more prone to the disease as compared to the females however the disorder in itself is rare in occurrence. Some of the major complaints seen in affected people are:

• Easy bruising
• Petechiae, i.e. red pinpoint spots on skin
• Low platelet count
• Episodes of nose bleeds
• Bloody diarrhea
• Recurrent bacterial and viral infections like herpes simplex virus, cytomegalovirus or Epstein-barr virus infections
• Associated autoimmune disorder like rheumatoid arthritis, and vasculitis
• Mucosal bleeding
• Red inflamed skin
• Cellulitis, impetigo, abscesses or other skin diseases
• Risk to develop lymphoma and other type of cancer

CAUSES of Wiskott Aldrich syndrome

WAS is inherited diseases through X-linked manner which occurs due to mutation in the WAS gene resulting in reduction in blood clotting ability and deficient immunity. Males are predominantly affected because they have only one X chromosome unlike females who have two so if one is affected the other healthy one can carry out the functions well. However this make females carrier of the disease so they can pass it to their children.

DIAGNOSIS of Wiskott Aldrich syndrome

Clinical presentation of the patient is the base of diagnosing the WAS disease which shows low platelets, count, mentioned ailments due to it and low levels of immunoglobulins. Family history is not found in all the cases as new mutations can occur. Bone marrow biopsy is done to rule out leukemia which is suspected due to the low platelet count and accompanied infections. The confirmation diagnostic test for WAS can be DNA sequence analysis which reveals the mutated genes and WAS disease.

TREATMENT of Wiskott Aldrich syndrome

In modern medicine the only method to cure this Wiskott Aldrich Syndrome is hematopoietic cell transplantation. However that can be way too costly and out of reach for many of the people. However you can manage this rare inherited disease by herbs and minerals formulations used in Ayurvedic system of medicine. Ayurveda can help in managing the Wiskott Aldrich Syndrome in a very natural method that even if used for long term do not causes any harm to the body and also convenient and within reach of everyone.

HERBAL REMEDIES BY PLANET AYURVEDA

There are certain herbal formulations which Planet Ayurveda offers to Manage Wiskott Aldrich Syndrome with Herbal Remedues. All these herbal formulations are free from chemicals, preservatives, colors, dye, fillers, additives and yeast and are purely vegetarian, natural and herbal. All the mentioned points make these herbo-mineral medications much more effective and safer than the other similar products present in the market. Planet Ayurveda has been serving the suffering people for more than a decade.

Product list

• Gandhak rasayan
• Immune booster
• Belgiri churna
• Sanjivani vati
• Pitta balance
• Kamdudha ras plain
• Spirulina capsule
• Suvarna basant malti ras
• Giloy capsule

Product Description

1. Gandhak Rasayan

Gandhak rasayan is prepared from the Purified sulphur (Shuddh gandhak). These herbal tablets help to treat the skin ailments like eczema, impetigo, inflamed and irritated skin. It clears the toxins from the blood and give healthy skin.

Dosage– Take 2 tablets twice daily after meals with plain water

2. Immune Booster Capsules

The main constituents of these capsules are Cow colostrums (Bovine colustrum), Bhumi amla (Phyllanthus niruri) Grape seed (Vitis vinifera), and Amalaki (Emblica officinalis). In WAS Immune booster capsules help to enhance the immunity and prevent disease caused due to lack of it.

Dosage– Take 1 capsule twice daily with plain water after meals

3. Sanjivani Vati

These herbal tablets prepared from herbs like Vidanga (Embelia ribes), Pippali (Piper longum), Ginger (Zingiber officinale), Vacha (Acorus calmus) etc is a Ayurvedic herbal preparation which ignites digestive fire, work as digestive, eliminate the endotoxins from the body, and help in maintaining healthy digestive system preventing and treating the digestive troubles caused in WAS. Sanjivani vaticlear the accumulated toxins the body effectively.

Dosage- 2 tablets twice daily with plain water after meals

4. Pitta balance

Pitta balance capsules helps in pacifying the aggravated Pitta which leads to ailments like bleeding disorders and low platelets. These amazing capsules help in combating bleeding, excessive heat, weakness, palpitations, etc. Pitta balance is a herbo-mineral capsule which are composed from natural calcium compounds that helps in cooling the body system like Kamdudha ras (Ayurvedic calcium compound), Akik pishti (Agate calcium), Praval pishti (Coral calcium), etc.

Dosage– Take 1 capsule twice daily after meals with plain water

5. Spirulina capsule

Spirulina capsules are a preparation of the blue-green algae i.e. Spirulina. These Ayurvedic formulated capsules are packed with minerals, vitamins, and other healthy components. Spirulina capsules are a natural form of Vitamin B12 and that helps in production of hemoglobin and healthy blood cells.

Dosage- Take 1 capsule twice daily after meals with plain water

6. Kamdhudha ras

Kamdudha ras is an Ayurvedic mineral formulation which works to maintain balance of Pitta dosha. Bleeding problems in WAS can be treated and managed effectively with these natural tablets. Kamdudha ras is prepared from Giloy (Tinospora cordifolia), Abhraka Bhashma (Mica bhasma), Shankh Bhashma (Conch bhasma), and Mukta bhasma (Pearl Calcium).

Dosage: – Take 1 tablet twice daily after meals with plain water

7. Suvarna basant malti ras

It is prepared from Suvarna bhasma (Gold bhasma), Shuddha hingula (Purified calx of zinc), Mukta bhasma (Pearl calcium) etc. Suvarna basant malti ras tablets help in boosting the immunity and prevent the disease caused due to its deficiency like bacterial, viral infections and autoimmune diseases.

Dosage- Take 1 tablet twice daily after meals with plain water.

8. Belgiri churna

Aegle marmelos is the main component of this herbal churna called Belgiri churna. It possesses all the qualities to maintain a healthy digestion and helps to treat the digestive ailment like diarrhes in WAS. Belgiri churna also possesses many nutritional properties that strengthen the digestive system of a person.

Dosage– Take 1 teaspoon twice daily after meals with plain water

9. Giloy Capsule

The standardized extract of the Tinospora cordifolia is used to prepare the amazing herbal Giloy capsules. These capsules are packed with many medicinal properties like enhances the platelets, boosts up the immunity, prevent the infections and autoimmune diseases which tends to occur in WAS.

Dosage- Take 1 capsule twice daily after meals with plain water

CONCLUSION

Wiskott Aldrich syndrome can be managed effectively with the mentioned herbal medicines as they consist of the effective herbs and minerals that possesses the abilities to manage genetic conditions like WAS. Ayurveda can be your safe and effective choice for managing the disorder that too in affordable limits.