Abstract What happens when the inflammatory signals driving Inflammatory Bowel Disease are interrupted at the cellular level? Ulcerative Colitis and Crohns Disease are chronic inflammatory disorders of the gastrointestinal tract that can cause diarrhoea, abdominal pain, urgency, rectal bleeding, fatigue and recurrent flares. As treatment strategies have evolved, attention has shifted from broad immune suppression towards therapies that target specific…
Abstract Ulcerative colitis is a chronic inflammatory bowel disease characterised by persistent inflammation of the colonic and rectal mucosa, commonly presenting with recurrent diarrhoea, rectal bleeding, abdominal discomfort, and urgency. Its development involves complex interactions among genetic susceptibility, immune dysregulation, gut microbiota, and environmental factors. The disease generally follows a relapsing and remitting course, with symptoms ranging from mild to…
Abstract Grahani & is anayurvedic name of digestive fire that means Agni which help to digest our food. Acharya Sushruta describes it, it is located between pakvasya and amasya and also known as Shashti pitta Dhara kala. WhenthisAgni is in a calm state or in ayurvedic term known as Manda Agni then body is unable to digest food and leads to…
Abstract Immunosuppressant drugs are those drugs which inhibit the action of the immune system. These drugs inhibit cellular or humoral or both immune responses and have a major role in autoimmune diseases, anticancer treatment and in organ transplantation. These drugs are class drugs which suppress or reduce the strength of the body’s immune system. Some names of the immunosuppressants are…