Regulating Inflammatory Mediators Using Yakrit Plihantak Churna


As we all know that nowadays the cases of liver disease are increasing every day because of sedentary habits.  One of the most common diseases is hepatic inflammation referred to as liver inflammation. It is a type of viral infection that is sometimes caused by an autoimmune disorder where the immune system of the body starts to attack the liver cells. The damage to the liver can also be caused by toxins, alcohol, or certain types of drugs that are responsible for activating the cytokines. One of these cytokines is TNF-alpha and IL-beta which is responsible for causing inflammation.  Here in this article, we are going to discuss how Yakrit Plihantak Churna help in regulating the inflammatory mediators and decreasing hepatic inflammation.

Hepatic Liver

What are TNF-Alpha and IL-Beta?

TNF-Alpha is basically a Tumor necrosis factor that is one of the cytokines or small proteins that are used by the immune system to signal the cells. When macrophages detect some infection they start to release TNF which then alerts the other immune cells as a part of the inflammatory response.

IL beta is known as Interleukin 1 beta or leukocytic pyrogen is also a cytokine protein or inflammatory cytokine that contains fever producing properties. This cytokine is also activated by the macrophages. It is involved in many cellular activities like apoptosis, cell proliferation, and differentiation.

What are the Symptoms of Hepatic Inflammation?

There are people that might not face any symptoms. But those who suffer from severe inflammation they might face these few signs and symptoms:-

  • Pain in abdomen
  • Weakness
  • Fatigue
  • Vomiting
  • Nausea
  • Yellow discoloration of the skin

What are the Causes for Hepatic Liver?

There are many reasons that can lead to an increase in the size of the liver and this includes:-

Problems of heart and blood vessel

  • Heart failure
  • Blockage of the veins present in the liver
  • Pericarditis


  • Leukemia
  • Lymphoma
  • Liver cancer

Liver Diseases

  • Hepatitis including A, B, and C.
  • NAFLD and AFLD
  • Wilson’s disease is a chronic disease where copper starts to accumulate in the liver.
  • Hemochromatosis
  • Liver cysts
  • Toxic hepatitis

Yakrit Plihantak Churna

Yakrit Plihantak churna is one of the best herbal remedies to treat liver disease and balancing the levels of TNF-Alpha and IL-Beta. It is made from eight types of herbs that help in protecting the liver. This is one of the best herbal remedies in detoxifying the liver and making the organ healthy. It is made from the herbs:-

  • Bhumi Amla (Phyllanthus niruri)
  • Bhringraj (Eclipta alba)
  • Kalmegh (Andrographis paniculata)
  • Sharpunkha (Tephrosia purpurea)
  • Kaasni (Cichorium intybus)

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How Each Herb Help in Protecting the Liver

1. Bhumi Amla (Phyllanthus Niruri)

Bhumi Amla is bitter and astringent in taste which is well known for containing antispasmodic, Anthelmintic, Anti-viral, and many other properties. It is well known for managing liver diseases and is also able to rejuvenate the liver as it also contains hepatoprotective. It will help in flushing out the toxins from the blood and making the liver healthy.

2. Bhringraj (Eclipta Alba)

Bhringraj is a special herb that is well known for treating the liver as it’s packed with antioxidant properties. This herb helps in improving the overall functioning of the liver and preventing swelling of the liver due to its anti-inflammatory and antibacterial properties. It helps in increasing the production of bile, removing toxins, and enhancing digestion as well. It is also very effective in improving liver enzymes and contains an antihepatotoxic effect.

3. Kalmegh (Andrographis Paniculata)

Kalmegh is a plant that is found mostly in countries like Sri Lanka and India. It is used for wide conditions but is specially indicated in liver conditions. It contains anti-inflammatory, antioxidant, and hepatoprotective properties. It is also useful in preventing the liver cells from getting damaged due to free radicals. It has also been found effective in treating liver infection, especially hepatitis B.

4. Sharpunkha (Tephrosia Purpurea)

It is one of the greatest medicinal herbs which is used for treating liver cirrhosis as well as splenomegaly. It contains agents which help in reducing swelling or inflammation  and also regulating blood sugar levels. Sharpunkha contains an agent that helps in detoxifying the liver and regenerating the liver cells.

5. Kaasni (Cichorium Intybus)

Kasni which is also known as chicory is known to be the best tonic for the liver. It is especially known for managing liver disorders like liver enlargement, jaundice, and fatty liver. It also works in balancing the Pitta Dosha and increasing the metabolism of the body by improving the digestive fire.


As discussed above in the article Yakrit Plihantak Churna is one of the best herbal medicines for treating Hepatic inflammation. Due to all the properties as discussed, each herb helps in balancing the levels of mediators like TNF-Alpha and IL-beta by removing toxins from the liver. Yakrit Plihantak Churna is proven to be the best herbal medicine to strengthen the liver.

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Dr. Vikram Chauhan (MD-Ayurvedic Medicine) is an expert Ayurveda consultant in Chandigarh (India). He has vast experience of herbs and their applied uses. He has successfully treated numerous patients suffering from various ailments, throughout the world. He is CEO and Founder of Krishna Herbal Company and Planet Ayurveda in Chandigarh, India. He researched age old formulas from ancient Ayurvedic text books to restore health and save human beings from the worst side-effects of chemical-based treatments.