How Ayurveda Can Help With Galloway-Mowat Syndrome?

ABSTRACT

As far as society is moving in today’s era of modernization, the prevalence rate of genetic disorder is also being raised due to the continuous mutation in the single or multiple genes or in the genomic sequence of our chromosomes. There are various types of genetic disorders such as- turner syndrome, down syndrome, marfan syndrome, thalassemias and galloway mowat syndrome. In this article let’s discuss the complete pathology behind Galloway-mowat syndrome and how ayurveda will help you in managing this.

INTRODUCTION

What is Galloway-mowat syndrome?

It is a type of genetic disorder in which a patient presents with various types of abnormalities mostly associated with neurological impairment and renal function variations.

In this ailment patient generally present with three main issues

• Small head circumference of infant as that of expected size (Microcephaly)
• Hiatus hernia (outward bulging of the part of stomach below the sternum)
• Nephrotic syndrome (damage to renal functions producing various symptoms like accumulation of lipid/fats in the blood channels)

ETIOLOGICAL FACTORS

It includes the factors responsible for giving rise to an ailment.

• Generally the cause is unknown.
• But according to the research it is considered as an autosomal recessive disorder means the defective gene is located on the autosome (there are 22 pairs of autosome and one pair of sex chromosome in our body).
• Genetic predisposition- Heredity also plays a major role in this.

CLINICAL FEATURES

It includes the complaints along with patient presents in front of a physician.

• Malformation of head circumference of the patient.
• Abnormal shapes of forehead are generally very high and narrow in appearance.
• A growth is seen in the thorax cavity of the infant.
• Repeated vomiting after ingestion of food.
• Indigestion.
• Sleep disturbance.
• Weight loss
• Anaemia
• Malnutrition
• Convulsion.
• Dyspnoea (difficulty in breathing)
• Visual impairments
• Abnormal muscles  spasm

DIAGNOSIS

The procedures a physician uses to diagnose the pathology of the disease.

• By detailed clinical examination of the patient by thorough inspection technique there will be presence of characterized physical findings in the patient.
• Laboratory test
• Renal function test
  • Haematuria (presence of blood in urine)
  • Proteinuria (presence of proteins in urine)
  • Albuminuria (albumin in the urine)
  • Hypoalbuminemia (low level of albumin in the blood)
• Genetic study

According To Ayurveda

The two most preferred diagnostic procedures used by a physician are as follow

Trividh pariksha (Group of 3 diagnostic procedures)

• Darsha – Diagnosis is made by visual examination of the symptoms.
• Sparshan – Physician uses tactile examination to evaluate whether skin is cold/hot
• Prashan – Physicians ask direct questions from the patient, to evaluate the root cause of the disease i.e. history taking.

 Asthavidh pariksha (set of 8 examination procedure)

• Nadi Pariksha – By palpating the pulse rate of the patient.
• Mutra Pariksha – By examining the urine of the patient.
• Mal Pariksha – By stool examination.
• Jivha Pariksha– By examining the tongue whether coated or not.
• Shabad Pariksha– By listening to the natural sounds within the body like intestinal sound (peristalsis) sounds of moving body fluids.
• Sparsh Pariksha – By observing the patient skin texture whether it is cool, wet or dry.
• Drik pariksha – When a physician inspects patient symptoms through his/her eyes.
• Akriti pariksha – When a physician evaluates the general appearance of a patient whether he/she looks dull, lethargic or fatigued etc.

MANAGEMENT

It included the whole line of treatment we can use in patients with galloway-mowat syndrome.

AS PER THE MODERN SYSTEM OF MEDICINE

• Intake of low sodium diet.
• In case of hypoalbuminemia- infusion of albumin is recommended.
• Use diuretics to aid in swelling associated with nephrotic syndrome of hypoalbuminemia- infusion of albumin is recommended.
• Use diuretics to aid in swelling associated with nephrotic syndrome
• Anticonvulsant drugs.

• The above mentioned treatment protocol just gives symptomatic relief to the patient but with the use of ayurveda we can easily manage the conditions like galloway mowat syndrome.

1. SANSHODHAN CHIKITSA (detoxification procedure)

• Deepan – In this the power of digestive fire (Agni) is increased by using deepan herbs such as saunf (fennel)
• Paachan – Digestive medicine is given by oral route to assimilate undigested food particles within the body.
• Sanehan – According to this smoothing the body doshas by using herbal ghrit/oil is done.
• Svedan – In this procedure the semi-hot medicated kwath (liquid medicine) is sprayed on the patient’s body by a specially made swedan yantra (instrument).
• Vaman (emesis) – emetic medicines are given to the patient to take out the vitiated dosha of the body.
• Virechan (purgation)- best treatment modality to remove excess pita dosha along with the stool from anal canal.

2. SAMSHMAN CHIKITSA (by medication)

In this we control the disease by subsiding doshas within the body itself by ingestion of medicines through oral route.

Herbal Remedies for Galloway-Mowat Syndrome by Planet Ayurveda

If you want to use orally, the herbal formulations, Planet Ayurveda a leading herbal manufacturing unit serving people worldwide with their herbal and authentic products offers various herbal formulations for this and are as follow

1. Punarnava Mandur
2. Reno Plan Syrup
3. Kumar Kalyan Ras
4. Neuro Plan Syrup
5. Digesto Plan Syrup

PRODUCTS DESCRIPTION

1. Punarnava Mandur

It is a classical formulationprepared using Punarnava (Boerhaavia diffusa), Pippali (Piper longum), Maricha (Piper nigrum), Amalaki (Emblica officinalis), Mandoor Bhasma (Ferric oxide calx) etc.This formulation is very effective in managing digestion related issues which a patient of galloway mowat syndrome usually suffers due to the presence of hiatus hernia.

Dosage: 1tablet two times a day with lukewarm water.

2. Reno Plan Syrup

This is a polyherbal formulation in syrup prepared using Punarnava (Boerhavia diffusa), bhumi amla (Phyllanthus niruri), gokshura (Tribulus terrestris), varuna (Crataeva nurvala), root extract of kash (Saccharum spontaneum), root extract of ikshu (Saccharum officinarum) etc. Herbs present in this work as a very good diuretic and clears out all the impurities present in the renal system of our body helps in dealing with symptoms of nephrotic syndrome, a common complaint of galloway mowat syndrome patients.

Dosage: 1 tsp two times daily after meal

3. Kumar Kalyan Ras

This is a classical tablet preparation made using Kumari rasa (Aloe vera), abhrak bhasma (purified and processed mica), mukta bhasma (calx of pearl), swarna bhasma (gold), shuddha parada (purified mercury) etc.This herbomineral formulation is a beautiful blend of various minerals and ghritkumari like herb, it is very good in digestive system related ailments like indigestion, emesis etc the most common complaints of a kumar (pediatric patients) so works really well in galloway mowat syndrome

Dosage: 1 twice daily with plain water or honey after meals.

4. Neuro Plan syrup

This syrup is safe and prepared using Brahmi (Bacopa monnieri), mandukaparni (Centella asiatica), shankhpushpi (Convolvulus pluricaulis), ashwagandha (Withania somnifera), bhojpatra (Betula utilis), marich (Piper nigrum), pippali (Piper longum) etc. Herbs in this formulation helps in strengthening the nervous system as they are good nervine tonic so aid in  complaints like convulsion, tremors of galloway mowat syndrome patients.

Dosage: 1 tsp twice daily after meal.

5. Digesto Plan Syrup

Digestoplan is a syrup preparation made up of  Ajwain (Trachyspermum ammi), amalaki (Emblica officinalis), haritaki (Terminalia chebula), sonth (Zingiber officinale, jeerak (Cuminum cyminum), dhanayak (Coriandrum sativum), shatapushpa (Antheum sowa) etc. This syrup piled up with the herbs that works really well in problems like indigestion, loss of appetite of a patient with galloway mowat syndrome

Dosage: 1 tsp two times a day after a meal.

CONCLUSION

We can now conclude that an ailment like galloway mowat syndrome needs to be treated as early as possible. So along with ongoing important treatment modalities we can use Ayurveda to combat the underlying associated symptoms such as vomiting, weight loss, weakness etc. For Ayurvedic treatment, you can consider choosing Planet Ayurveda as we have been serving the mankind with our holistic approach of healing.