ABSTRACT Systemic sclerosis is a chronic autoimmune connective tissue disorder where the skin serves as both a mirror and a marker of internal disease. The tightening, thickening, and hardening of the skin not only reflect the pathological process of excessive collagen deposition but also provide the earliest and most visible clues to diagnosis. Beyond being a protective barrier, the skin…
Abstract Fibromyalgia is a mysterious and often misunderstood disorder that turns everyday sensations into relentless pain, affecting muscles, joints, and nerves. Affecting millions worldwide, it is more than just “aches and fatigue”—it’s a disruption in the body’s pain processing system. Abnormal nerve signaling, heightened sensitivity of the central nervous system, and subtle muscle dysfunction combine to create a constant cycle…