Abstract Genetic neurodegenerative disorders comprise a diverse group of inherited conditions characterized by the progressive degeneration of neurons, leading to impairment of motor, sensory, cognitive, and other neurological functions. Among these disorders, Spinocerebellar Ataxia Type 12 (SCA12) is a rare autosomal dominant condition that primarily affects the cerebellum, resulting in progressive tremors, ataxia, impaired coordination, and speech disturbances. SCA12 is…